Are you suffering from constant muscle weakness? It may be a sign of peripheral neuropathy. Some other common symptoms of peripheral neuropathy include loss of coordination, burning pain, numbness, increased sensitivity to touch in your arms and legs.

Peripheral neuropathy is a collective term defining the damage to nerves due to multiple health conditions like autoimmune diseases, deficiency of Vitamin B12, diabetes, infections, etc.

Although some types of peripheral neuropathy cannot be entirely cured, starting treatment at an early stage can prevent further damage. The nerves may regenerate and give improved symptoms. A supplement that has shown effectiveness in treating painful diabetic neuropathy is Benfotiamine.

 

 

 

What Is Benfotiamine?

 

Benfotiamine is a synthetic derivative of Thiamine or Vitamin B1, which can be prepared from plants such that of garlic and onion. Due to the chemical changes being made, it has shown better absorption results than thiamine itself. It has been effective in treating peripheral neuropathy, specifically the one caused by alcohol and diabetes.

 

 

 

Benfotiamine Treats Peripheral Neuropathy

 

Thiamine of Vitamin B1 has proved its efficacy in treating nerve pain and inflammation by increasing the process of nerve repair. It allows the nerve to function better and regenerate.

Likewise, Benfotiamine has also shown positive results in treating diabetic polyneuropathy, as a recent study suggested improved vibratory sensations in a patient who was supplemented. Similarly, a placebo-controlled clinical study marked the efficacy and safety of Benfotiamine in reducing pain and improving the condition.

Research suggests that Benfotiamine has a protective effect against the oxidative damage caused by the AGEs. These advanced glycation end products are the lipids and proteins that become glycated as a result of impaired glucose metabolism in diabetes type-2 and then cause nerve damage.

Furthermore, it has been seen through research that Benfotiamine has failed to show results in patients with type-1 diabetes even after being supplemented with a high dose of 300mg per day.

A study was done to analyze the effect of opioids and Benfotiamine collectively on a diabetic mouse. It showed that the supplement improved the analgesic effect of mu-opioid agonists in treating neuropathic pain.

Another random experiment on 9 diabetic patients showed that when they were supplemented with Benfotiamine, Vitamin B6, and B12, there was an improvement in the conduction velocity of the nerves.

Benfotiamine Supplement relieves nerve pain and aids in the regeneration of new nerve cells. It increases the nerves' functional capacity and sometimes might reverse the nerve degeneration that is causing peripheral neuropathy. The supplement is recommended by various doctors and physicians

 

 

The Takeaway

Peripheral neuropathy is a manageable disease. You can reduce the symptoms and prevent further degeneration of the nerves by following specific guidelines. This also includes adding Benfotiamine supplements to your diet. The information mentioned above supports it through various studies.

 

 

References

1. Haupt. E., Ledermann, H.. & KOpcke, W. (2005). Benfotiamine in the treatment of diabetic polyneuropathy--a three-week randomized, controlled pilot study (BEDIP study). International journal of clinical pharmacology and therapeutics, 43(2), 71-77. https://doi.org/10.5414/cpp43071 

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