The Advantages of Using Exosomes in Treating Diseases

Exosomes are vesicles that are generated by cells extracellularly, and they contain lipids, metabolites, and proteins. They are used to mediate intercellular communications in diseases and health, which then affects the biological composition of cells in the body.

Exosomes have been known to treat diseases such as cancer by providing "vehicles" which are used to deliver cancer drugs to affected body cells. Doctors also use them to develop therapies that are responsible for treating different ailments depending on the degree of severity of a patient.

So, what are some of the advantages of using exosomes in disease treatment? They include the following;

 

They Are Compatible with Living Cells and Tissues.

When an exosome fuses with a cell membrane, its contents are fully released into the cytoplasm. While this route is the most efficient, there is clear evidence indicating that the mechanism responsible for compatibility is endocytosis. Endocytosis involves an exosome being engulfed by a plasma membrane, which in turn joins the endosomal system.

 

They Exhibit Low Toxicity.

One reason why exosomes hold potential in therapeutics is because they have low toxicity levels. They are also able to cross the barrier caused by blood-brain for maximum potential in treating ailments.

Another factor to consider is that they have a reduced threat against the self-exosomes, and they also have a membrane which is stable and ensures their uptake in facilitating transportation from one cell to the other.

 

They Help in Extending Blood Circulation.

Exosomes play a huge role in helping in the circulation of blood throughout the body. When exosomes are secreted, they become so small that they can easily enter the blood circulation through the gaps located in the endothelial cells.

Once they pass the endothelial cells, they are disseminated to various organs in the body and cells, hence boosting and extending blood circulation in the body.

 

They Are Excellent Therapeutic Carriers.

Exosomes, which are secreted by different types of cells, are known to carry molecules which act as signals. The molecules include proteins and nucleic acid.

The secreted exosomes play a vital role in the behaviour of cells. Since they are best adapted for intercellular correspondence in the body, they help deliver drugs to cells that need them.

In conclusion, exosomes play a huge role in ensuring that body functions work out well, ranging from blood circulation to merging with living cells and tissues. The above advantages are vital in ensuring diseases are not only treated well and effectively but also in a timely manner to ensure the survival of patients.

Sources

1.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865231/#:~:text=Exosomes%20secreted%20by%20different%20types,therapeutic%20drugs%20to%20target%20cells.

2.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658823/#:~:text=Exosomes%20present%20many%20advantages%2C%20such,them%20an%20excellent%20therapeutic%20carrier.

3.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717626/#:~:text=Exosomes%20are%20extracellular%20vesicles%20generated,various%20aspects%20of%20cell%20biology.

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